CAR-T Therapy Cures Stiff Person Syndrome:...

Kyverna Therapeutics' miv-cel CAR-T therapy successfully treated Stiff Person Syndrome in a Phase 2 trial: 81%! Swipe to see →

CAR-T THERAPY CURES STIFF PERSON SYND...

On April 21, 2026, at the American Academy of Neurology annual meeting, researchers from Kyverna Therapeutics presented data that fundame...

WHAT IS STIFF PERSON SYNDROME?

Stiff Person Syndrome is one of the rarest and most misunderstood diseases in neurology. Affecting approximately 1 in 1 million people gl...

THE EXISTING TREATMENTS AND THEIR LIM...

Before 2026, treatment for SPS relied on a handful of approaches, none of which addressed the underlying cause:

HOW CAR-T THERAPY WORKS DIFFERENTLY

CAR-T (Chimeric Antigen Receptor T-cell) therapy represents a fundamentally different approach. Instead of suppressing the immune system ...

THE KYSA-8 TRIAL: RESULTS THAT CHANGE...

The KYSA-8 Phase 2 clinical trial enrolled 26 patients with moderate-to-severe SPS who had failed or were inadequately controlled on exis...

WHY THIS IS HISTORICALLY SIGNIFICANT

The KYSA-8 results matter for several reasons that extend beyond SPS itself:

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